Data management of protein interaction networks


Mario Cannataro, Pietro Hiram Guzzi.
Bok Engelsk 2012 · Electronic books.
Omfang
1 online resource (226 p.)
Opplysninger
Description based upon print version of record.. - Frontmatter -- Color Plates -- Interactomics -- Technologies for Discovering Protein Interactions -- Graph Theory and Applications -- Protein-To-Protein Interaction Data -- Protein-To-Protein Interaction DATABASES -- Models for Protein Interaction Networks -- Algorithms Analyzing Features of Protein Interaction Networks -- Algorithms Comparing Protein Interaction Networks -- Ontology-Based Analysis of Protein Interaction Networks -- Visualization of Protein Interaction Networks -- Case Studies in Biology and Bioinformatics -- Future Trends -- References -- Index.. - "Current PPI databases do not offer sophisticated querying interfaces and especially do not integrate existing information about proteins. Current algorithms for PIN analysis use only topological information, while emerging approaches attempt to exploit the biological knowledge related to proteins and kinds of interaction, e.g. protein function, localization, structure, described in Gene Ontology or PDB. The book discusses technologies, standards and databases for, respectively, generating, representing and storing PPI data. It also describes main algorithms and tools for the analysis, comparison and knowledge extraction from PINs. Moreover, some case studies and applications of PINs are also discussed"--
Emner
Sjanger
Dewey
ISBN
1-118-10371-8. - 1-118-10373-4. - 1-118-10374-2. - 1-280-67506-3. - 9786613651990

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