The stages of Alzheimer's disease: A reappraisal
H.C. Kraemer
Bok Engelsk 1998
| Utgitt | 1998
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|---|---|
| Omfang | Side 299- 308
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| Opplysninger | 'Stages', as used in clinical practice and research, are defined,their value described, and criteria are proposed for theirevaluation. The specific interest is in staging Alzheimer's disease(AD). Two staging systems, one based on the Global DeteriorationScale (GDS) and one based on the Mini-Mental State Exam (MMSE), arecompared in terms of these criteria, as an illustration of theprocess involved. We propose that there is not one unique stagingsystem, that different staging criteria might be appropriate todifferent research or clinical needs, depending on which part of thetemporal course of the disease is of primary interest, and on whetherthe focus is on cognitive, functional, neurological, behavioral,economic, or other issues. GDS staging seems a better choice for thelater stages of AD when the focus is on functional change. MMSEstaging seems a better choice for tracking the earlier stages of ADwhen the focus is on cognitive change.
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| Emner |
