Cognitive test scores in community-based older adults with andwithout dementia


M. Ganguli
Bok Engelsk 1997
Utgitt
1997
Omfang
Side 176- 180
Opplysninger
In an epidemiological survey of a rural, largely blue-collar,community, 1,363 randomly selected adults, aged 65 + years, wereadministered a cognitive screening battery (including in part theCERAD neuropsychological tests): Mini-Mental State Examination; WordList Learning, Recall, and Recognition; Story, Immediate and DelayedRecall; Boston Naming Test; Verbal Fluency; Temporal Orientation;Constructional Praxis; Draw a Clock; and Trailmaking. Cognitivelyimpaired subjects and cognitively intact controls underwentindependent standardized diagnostic assessments and were rated onClinical Dementia Rating (CDR) scale. Overall, subjects at higher CDRlevels (more severe dementia) had worse scores on all tests; showingthat standard neuropsychological tests are valid for characterizingthe cognitive impairments seen in dementia, even in communitysettings. However, non-demented scores on the CERAD tests in thiscommunity-based sample were lower than reported from CERAD's pooledhealthy controls from Alzheimer's Disease Centers (ADCs) nationwide.Thus, 'normal' scores from specialty dementia clinics, where theremay be a selection bias, may differ from normative scores from ruraland/or less-educated populations. Patients from such populations maybe functionally intact despite low test scores. Community-basedstudies are required to complement specialty clinic-based studies ofdementia and cognitive functioning.
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