The use of selective serotonin reuptake inhibitors for depression andpsychosis complicating dementia
W.J. Burke
Bok Engelsk 1997
| Utgitt | 1997
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|---|---|
| Omfang | Side 519- 525
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| Opplysninger | This retrospective chart review examines the impact of selectiveserotonin reuptake inhibitors on 20 patients with both depression andpsychosis complicating dementia of the Alzheimer type (DAT) and otherdementias. Fifteen of the 20 patients had moderate to markedimprovement in depressive and psychotic symptoms. Eleven of 12patients with DAT had moderate to marked improvement compared to onlyfour of eight patients with dementia from other causes. The drugswere effective in diminishing or eliminating psychotic symptoms insix patients who had previously not responded to a trial of aneuroleptic. The selective serotonin reuptake inhibitors may have animportant role to play in patients with DAT who have coexistingdepression and psychosis. These drugs are very well tolerated and mayhave a place as first-line agents in non-emergent settings where aclinician might otherwise think of instituting a neuroleptic or as asec-end-line agent when a neuroleptic has proven ineffective. (C)1997 by John Wiley & Sons, Ltd.
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| Emner |
