Quantitative electroencephalography power and coherence inAlzheimer's disease and mild cognitive imp - detaljert visning

Quantitative electroencephalography power and coherence inAlzheimer's disease and mild cognitive impairment

V. Jelic
Bok Engelsk 1996


Utgitt	1996
Omfang	Side 314- 323
Opplysninger	In this study the best combination of quantitativeelectroencephalographic variables (qEEG) for the discrimination ofgroups with mild to moderate Alzheimer's disease (AD), mild cognitiveimpairment and healthy subjects was defined and related toneuropsychological performance. The study population included 18patients with mild to moderate probable AD, 19 subjects withobjective memory disturbances, 17 subjects with subjective memorycomplaints who did not have clinical evidence of memory disturbance,and 16 healthy controls. AD patients had significantly increasedtheta and decreased alpha relative power, mean frequency, andtemporoparietal coherence. There was no significant difference in themean frequency in the left temporal region between AD patients andsubjects with objective memory disturbances. Temporoparietalcoherence appeared as a discriminant variable together with alpha andtheta relative power only between AD patients and controls, giving77.8% sensitivity and 100% specificity, Significant correlationsbetween regional changes in qEEG variables and cognitive functionswere found.
Emner	Alzheimer's disease Clinical Diagnosis DECLINE DETERIORATION Vis mer... Depression Discriminant Analysis EEG coherence EEG power FOLLOW-UP FREQUENCY-ANALYSIS Memory PATTERNS RESTING AWAKE EEG SENILE DEMENTIA mild cognitive impairment quantitative electroencephalography