Carbamazepine use in aggressive behaviour associated with seniledementia
C. Cooney
Bok Engelsk 1996
| Utgitt | 1996
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|---|---|
| Omfang | 4 s.
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| Opplysninger | In a randomized placebo crossover controlled study, six patients meeting DSM-III-R criteria for Alzheimer's disease and exhibiting significantly aggressive behaviour were administered carbamazepine(in doses up to 600 mg daily) and placebo, with each treatment period lasting 8 weeks. Levels of aggression as measured by the RAGE scale were significantly reduced compared with placebo (p < 0.05). The results suggest that carbamazepine is an effective antiaggressiveagent in patients with dementia. Recommendations for further studies are made.
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| Emner |
