Electroencephalographic correlates of periventricular white matter lesions in probable alzheimer's d - detaljert visning

Electroencephalographic correlates of periventricular white matter lesions in probable alzheimer's disease

O.L. Lopez
Bok Engelsk


Utgitt	OL Lopez Neuropsychol Res Program 3600 Forbes
Opplysninger	We evaluated the relationship between periventricular white matter lesions (PWMLs) and EEG abnormalities in probable Alzheimer's disease (AD). We visually analyzed the EEG of 27 probable AD patients with mild to moderate degree of cognitive impairment participating in a longitudinal study of dementia. Patients had both CT and MRT scans performed at baseline examination, which also included an EEG. PWMLs were rated in CT and MRI films using a semiquantitative method. The EEGs were classified according to the Mayo Clinic Classification System. Abnormal EEGs correlated with PWMLs rating scores were detected on CT, but not on MRI. These data suggest that the presence of PWMLs contribute to the abnormal EEGs observed in AD patients, and that white matter abnormalities in CT correlate better with both the clinical findings and EEG than does the more sensitive but less specific MRI.
Emner	Alzheimer's disease BRAIN LUCENCIES CT Cognition Vis mer... Dementia Diagnosis, Differential EEG EEG FINDINGS Hyperintensities Leukoaraiosis Leukoencephalopathy Vascular dementia White matter lesions
ISSN	1013-7424