Acute delirium and functional decline in the hospitalized elderly patient
Anne M. et al. Murray
Bok Engelsk 1993
| Utgitt | 1993
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| Omfang | 6 s.
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| Utgave | Særtrykk/Kopi
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| Opplysninger | Abstract Background: Delirium is often considered a transient syndrome. It effect on long-term physical function, however, has not been well defined.Methods: In prospective study of 325 hospitalized community and nursing home elderly, we analyzed the effect of inhospital delirium on subsequent physical function. ADL performance was assessed prior to admission, and at 3 and 6 months after hospital discharge.Results: There was a strong univariate (unadjusted) association between incident delirium and functional decline (p<.02) Delirious subjects lost mean of almost one ADL, as measured 3 months after hospital discharge. Using multivariate linear regression analysis, with adjusted change in function as the dependent variable, delirium persisted as the sole predictor of loss of function (p=.009) at 3 months after discharge. The functional decline persisted at 6 months after hospital discharge.Conclusion: This finding of a nontransient. perhaps permanent consequence of delirium invites reexamination of the definition of delirium from that of an acute, reverible syndrome to one of acute onset with long-term sequelae.
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