Phagocytes and cellular immunity


Hans H. Gadebusch, editor.
Bok Engelsk 2019 · Electronic books.
Medvirkende
Omfang
1 online resource.
Opplysninger
Cover -- Title Page -- Copyright Page -- Preface -- Introduction -- The Editor -- Contributors -- Dedication -- Table of Contents -- Phagocytes by Human Neutrophils -- I. Introduction -- II. Stages IA and IB: Production and Mobilization of Neutrophils Into Blood-stream -- III. Stages IC to IF: Approach of The Neutrophil to The Bacteria -- A. Stage IC: Alterations in Vascular Permeability -- B. Stage ID: Adherence of Neutrophils to Blood Vessel Wall -- C. Stage IE: Emigration of Neutrophils Into Tissues -- D. Stage IF: Chemotaxis -- 1. Assays for Chemotaxis -- 2. Chemotactic Substances -- IV. Stages IIA to IIC: Factors Relating to Ingestion of Bacteria -- A. Stage IIA: Opsonization of B Acteria -- B. Stage IIB: Adherence of Neutrophil to Bacteria -- C. Stage IIC: Ingestion of Bacteria by Neutrophil -- 1. Measurement of Phagocytosis -- 2. Role of Divalent Cations -- 3. Physical Forces Affecting Phagocytosis -- 4. Relationship of Metabolism to Ingestion -- V. Stages IID to IIG: Factors Relating to Bactericidal Activity -- A. Stage IID: Increased Oxidative Metabolism -- 1. Events Involved in the Respiratory Burst -- 2. Clinical Syndromes with Defective Respiratory Burst -- 3. Biochemical Basis of the Respiratory Burst -- B. Stage IIE: Degranulation -- 1. Composition of Granules -- 2. Dynamic Aspects Of Degranulation -- C. Stages IIF and IIG: Killing and Digestion of Bacteria -- 1. Mechanisms Involving H[sub(2)]O[sub(2)] Production. -- 2. Mechanisms Involving Free-Radical Forms of Oxygen -- 3. Oxygen-Independent Mechanisms -- Acknowledgments -- References -- Macrophages As Effectors of Cell-Mediated Immunity -- I. Introduction -- A. Characteristics of the Mononuclear Phagocytic System -- II. Participation of Macrophages in Cell-Mediated Immunity -- A. Antimicrobial Immunity -- 1. Bacteria and Fungi -- 2. Viruses -- 3. Protozoa and Metazoa.. - B. Transplantation Immunity -- C. Tumor Immunity -- D. Autoimmunity -- III. Mode of Action of Macrophages as Effectors of Cell-Mediated Immunity -- A. Antimicrobial Immunity -- B. Anticellular Immunity -- IV. Lymphocyte-Macrophage Cooperation in Cell-Mediated Immunity -- A. Delayed-Type Hypersensitivity As A Model -- B. Antimicrobial Immunity -- C. Anticellular Immunity -- V. Regulatory Roles of Macrophages -- A. Immunological Phenomena -- B. Inflammatory Reactions -- C. Surveillance Against Neoplasia -- VI. Human Monocytes and Macrophages -- References -- Host-Parasite Interactions with Macrophages in Culture -- I. Introduction -- II. Heterogeneity -- III. Maintenance in Culture -- IV. Metabolic Analysis -- V. Phagocytosis -- VI. Macrophage-Parasite Interactions -- VII. Conclusions -- References -- Native and Acquired Resistance to Infection With Cryptoccoccus Neoformans -- I. Introduction -- II. The Naturally Acquired Infection -- A. The Initial Encounter -- B. Cellular Reaction to Pathogen Deposition -- III. Pulmonary Response to Fungemic Challenge -- IV. The Peritoneal Cavity As A Model Site for The Study of Host-Parasite Interaction -- A. Genesis of the Host Response -- B. Chemotaxis -- C. Phagocytosis -- 1. Interiorization of C. Neoformans -- 2. Intracellular Fate of The Pathogen -- D. Extracellular Destruction of Cryptococci -- 1. Secretion of Lysosomal Enzymes -- 2. Anticryptococcal Substances: Lysosomal -- 3. Anticryptococcal Substances: Nonlysosomal -- 4. Cytoxicity of Cationic Cell Proteins -- 5. Antibody-Dependent Cell-Mediated Cytotoxicity -- V. Acquired Immunity -- A. Historical Background -- B. Role of Anticryptococcal Antibody -- C. Role of Cell-Mediated Immunity -- VI. Dissemination of Pathogens from Primary Sites of Infection -- VII. Predilection of Pathogen for Central Nervous System -- VIII. Concluding Remarks -- References.. - Index.. - First Published in 1979: Each of the first two papers deal with the particular cellular component and its role in containing appropriate pathogen.
Emner
Sjanger
Dewey
ISBN
0-429-27657-5. - 1-000-46832-1. - 1-000-47788-6

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