Advances in health and disease. Volume 21 /.
Lowell T. Duncan, editor.
Bok Engelsk 2020 · Electronic books.
Medvirkende | Duncan, Lowell T., (editor.)
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Utgitt | Nova Medicine and Health
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Omfang | 1 online resource (260 pages).
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Opplysninger | Intro -- Contents -- Preface -- Chapter 1 -- The Impact of Polypharmacy on Health and Quality of Life for Older Adults -- Abstract -- Introduction -- Scope of the Problem -- Medical Polypharmacy -- Psychiatric Polypharmacy -- Anticholinergic Burden -- Psychotropic Medication Misuse and Noncompliance -- Other Patient Factors that Contribute to Polypharmacy -- Medication Compliance and Cost -- Herbals and Dietary Supplements -- Polypharmacy Problems Specific to Older Adults -- Non Pharmacologic Interventions to Reduce Polypharmacy -- Lifestyle Improvements -- Weight Loss -- Nutrition and Diet Quality -- Exercise -- Sleep Improvement -- Tobacco Cessation -- Alcohol Misuse Management -- Treatment of Depression and Anxiety -- Patient and Family Education -- Improve Prescriber Education -- Conclusion -- References -- Chapter 2 -- A Closer Look at Generic Drugs: The Brazilian Case -- Abstract -- 1. Overview of Generic Drugs in Brazil -- 2. Historical Overview of Generic Drugs in Brazil -- 2.1. National Medicines Policy, Generic Drugs Law and Incentive Measures -- 3. Generic Drug Market in Brazil -- 4. Market Access to Drugs in Brazil -- 5. The Backlog on Drug Patents in Brazil -- 6. Interchangeability of Nonbioequivalent Drugs -- 7. Perceptions of the Population Regarding Generic Drugs in Brazil -- Conclusion - Perspectives for the Future -- References -- Biographical Sketch -- Chapter 3 -- Occurrence and Bioactivity of Phytochemicals and Their Role in Human Health -- Abstract -- 1. Introduction -- 2. Phytochemicals Research -- 3. Possible Ways of Phytochemicals Action -- 3.1. Antioxidant -- 3.2. Hormonal Action -- 3.3. Interference with DNA Replication -- 3.4. Enhancement of Enzymes -- 4. Benefits of Phytoconstituents in Health -- 5. Classes of Phytoconstituents -- 5.1. Terpenoids -- 5.1.1. Tocotrienols and Tocopherols -- 5.1.2. Carotenoids.. - 5.1.3. Limonoids -- 5.1.4. Phytosterols -- 5.2. Phenolic Compounds -- 5.2.1. Flavonoids -- 5.2.2. Tannins -- 5.2.3. Stilbenes -- 6. Role of Phytoconstituents in the Treatment of Disease -- 6.1. Phytochemicals (Phenolic and Flavonoids) as Therapeutic and Anti-Cancer Agents -- 6.2. Cardiovascular Disease -- 6.2.1. Phloretin -- 6.2.2. Lycopene -- 6.3. Cancer -- 6.3.1. Curculigo Orchioides -- 6.3.2. Glycyrrhiza Glabra -- 6.3.3. Callistemon Lanceolatus -- 6.3.4. Achyranthes Aspera -- 6.3.5. Piper Longum -- 6.3.6. Mallotus Philippinensis -- 7. Rheumatoid Arthritis -- 7.1. Arnica Montana -- 7.2. Centella Asiatica -- 8. Effect of Phytochemicals on Stem Cells -- 8.1. Ursolic Acid -- 8.2. Cirsimaritin -- 8.3. Artepillin C -- 8.4. Reseveratol -- 8.5. Curcumin -- 8.6. Sulforaphane -- 9. Traditional Therapies and Phytochemicals in Wound Healing -- 9.1. Curcumin -- 9.2. Rutin -- 9.3. Berberine -- Conclusion -- Conflict of Interest -- References -- Chapter 4 -- For Better and for Worse: A Molecular Perspective of the Comparative Biological Functions of NF-κB in Human Health and Diseases -- Abstract -- Introduction -- Different Pathways Activating NF-κB Signals -- NF-κB Role in Human Health -- NF-κB Role in Human Diseases -- Atherosclerosis -- Cardiovascular Diseases -- Asthma -- Neurodegenerative Diseases -- Cancer -- Drug/Chemical-Induced Organ Toxicities -- NF-κB as a Therapeutic Target -- Anti-Inflammatory -- Neurodegenerative Therapy -- Differential Role of NF-κB and JNK Signaling Cascades -- Conclusion -- References -- Biographical Sketch -- Chapter 5 -- Changing Paradigms in the Pathophysiology of CSF Dynamics -- Abstract -- Introduction -- Historical Importance -- Bulk Flow Model and Circulation Theory -- The Implication of Changing the Concept -- Evolving Concepts in the Pathophysiology of CSF Dynamics -- Hyperosmolarity Model of Hydrocephalus.. - CSF Lymphatic System Model -- Hydrodynamic Model of Hydrocephalus -- Genetic Causes of Hydrocephalus -- Disorder of the Venous System -- Post-Traumatic Hydrocephalus -- Post Subarachnoid Hemorrhage Hydrocephalus -- Post-Tubercular Hydrocephalus - Unmet Need of Understanding Pathogenesis -- Hydrocephalus in an Aging Brain -- Conclusion -- References -- Chapter 6 -- Non-Exudative Age-Related Macular Degeneration: New Experimental Insights -- Abstract -- 1. Non-Exudative Age-Related Macular Degeneration -- 1.1. A New Model of Non-Exudative Age-Related Macular Degeneration Induced by Superior Cervical Ganglionectomy -- 2. Regional RPE Attributes from Naïve Animals That Could Account for the Regional Susceptibility within NE-AMD -- 3. Localized Oxidative Stress and Mitochondria Damage at Early SCGx-Induced NE-AMD -- Conclusion -- References -- Chapter 7 -- Pediatric Isolated Fallopian Tube Torsion -- Abstract -- Introduction -- Anatomy of the Fallopian Tubes -- Isolated Fallopian Tube Torsion -- Definition -- Ethiology -- IFTT and Hydrosalpinx -- Incidence -- Symptoms -- Radiological Examinations -- Differential Diagnosis -- Surgical Therapy -- Conclusion -- References -- Biographical Sketch -- Chapter 8 -- Post-Cerebral Infarction Seizures -- Abstract -- 1. Burden of Epilepsy in Stroke -- 2. Classification of Seizures in Stroke -- 3. Pathogenesis of PSS -- 4. Risk Factors of Seizures -- 5. Clinical Manifestations and Diagnosis of PSS -- 6. Role of Prophylactic Anti-Convulsants -- 7. Treatment of PSS and PSE -- 8. Duration of AED after Ischemic Stroke -- Conclusion -- References -- Contents of Earlier Volumes -- Index -- Blank Page.
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ISBN | 1-5361-7784-9
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