Overtime reliability of medial temporal lobe atrophy rating in a clinical setting
L. Cavallin L. Cavallin, K. Løken, Knut Engedal, Anne Rita Øksengård, LO Wahlund, L. Bronge, R Axelsson
Bok 2012
| Utgitt | 2012
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| Omfang | 5 s.
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| Opplysninger | Medial temporal lobe atrophy (MTA) is one of the first magnetic resonance imaging (MRI) signs in patients with Alzheimer's disease (AD) and used as a measure of disease progression. Visual assessment of MTA is easy to perform but the reliability of MTA rating over time has not been studied. To investigate what happens to the MTA rating scores if two radiologists rate the same MRI scans six times over a period of 1 year. One hundred outpatients were included in this study. All patients underwent MRI with a protocol and sequences used for geriatric patients, according to local clinical standards. One neuroradiologist and one general radiologist independently of each other performed retrospective visual assessments of MTA six times, using the same scans, over a period of 1 year.
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