Frontal lobe degeneration and Alzheimer's disease: A controlled studyon clinical findings, volumetric brain changes and quantitativeelectroencephalography data
H. Forstl
Bok Engelsk 1996
| Utgitt | 1996
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|---|---|
| Omfang | Side 27- 34
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| Opplysninger | Ten patients with a clinical diagnosis of frontal lobe degeneration(FLD) were compared with a group of patients with probableAlzheimer's disease (AD) and with nondemented controls matched forgender and age. In comparison with AD, the duration of illness wasslightly shorter and cognitive performance was better in patientswith FLD. The greatest enlargement of cerebrospinal fluid volumes wasfound in FLD and this effect was most pronounced in the anteriorfissure and lateral ventricles. Estimates of EEG band-power and EEGcoherence in FLD were not remarkably different from nondementedcontrols, whereas delta- and theta-power were significantly increasedin AD. These observations may indicate different disease processeswith a dissociation of volumetric computed tomography andquantitative EEG changes, which may be of differential diagnosticvalue.
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| Emner |
