Improving the diagnostic accuracy of the mini-mental state examination
A.U. Monsch
Bok Engelsk 1995
| Utgitt | AU Monsch Univ Basel Hosp Geriat Hosp Memory , 1995
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| Opplysninger | Introduction - We determined the diagnostic accuracy of the Mini-Mental State Examination (MMSE) for dementia of the Alzheimer type (DAT) in an outpatient geriatric referral center in Switzerland. Material & methods - DAT patients and elderly controls were assigned to two groups: a validation sample (70 DAT patients; 50 controls) and a cross-validation sample (133 DAT patients; 43 controls). A Receiver Operating Characteristic curve was generated to derive the optimal MMSE cut-off score in the validation sample. Results - The optimal MMSE cut-off was <26/30 (sensitivity of 74%, specificity of 100%). Adjustments for age and education were necessary. The cross-validation confirmed these findings. Conclusion - In a clinical setting the MMSE cut-off should be increased to <26/30. A thorough neurobehavioral assessment is still necessary for a complete evaluation.
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