THA - historical aspects, review of pharmacological properties and therapeutic effects - detaljert visning

THA - historical aspects, review of pharmacological properties and therapeutic effects

J.C. Soares
Bok Engelsk


Utgitt	JC Soares Univ Pittsburgh Western Psychiat Ins
Opplysninger	The authors reviewed historical data in the development of THA, as well as recent data on its pharmacological properties and therapeutic effects on cognitive dysfunction. A medline search was conducted to identify the trials conducted with THA in Alzheimer's disease (AD) patients. The findings seem to lend support to some palliative action of THA, especially at higher doses, but in these doses about 2/3 of the patients experience significant adverse reactions. The significance of these findings is discussed, with emphasis on the their relevance for the management of AD patients.
Emner	Alzheimer's disease CLINICAL-RESPONSE Dementia Double-blind method Vis mer... Lecithin MULTICENTER TRIAL ORAL TETRAHYDROAMINOACRIDINE Pharmacotherapy SENILE DEMENTIA TACRINE HYDROCHLORIDE THA Tetrahydroaminoacridine cognitive dysfunction CEREBRAL BLOOD-FLOW therapeutics
ISSN	1013-7424