NMR Spectroscopy Explained : Simplified Theory, Applications and Examples for Organic Chemistry and Structural Biology


Neil E. Jacobsen
Bok Engelsk 2007 · Electronic books.
Utgitt
Hoboken : : Wiley, , 2007.
Omfang
1 online resource (686 p.)
Opplysninger
Description based upon print version of record.. - NMR SPECTROSCOPY EXPLAINED; CONTENTS; Preface; Acknowledgments; 1 Fundamentals of NMR Spectroscopy in Liquids; 1.1 Introduction to NMR Spectroscopy; 1.2 Examples: NMR Spectroscopy of Oligosaccharides and Terpenoids; 1.3 Typical Values of Chemical Shifts and Coupling Constants; 1.4 Fundamental Concepts of NMR Spectroscopy; 2 Interpretation of Proton ((1)H) NMR Spectra; 2.1 Assignment; 2.2 Effect of B(o) Field Strength on the Spectrum; 2.3 First-Order Splitting Patterns; 2.4 The Use of (1)H-(1)H Coupling Constants to Determine Stereochemistry and Conformation; 2.5 Symmetry and Chirality in NMR. - 2.6 The Origin of the Chemical Shift2.7 J Coupling to Other NMR-Active Nuclei; 2.8 Non-First-Order Splitting Patterns: Strong Coupling; 2.9 Magnetic Equivalence; 3 NMR Hardware and Software; 3.1 Sample Preparation; 3.2 Sample Insertion; 3.3 The Deuterium Lock Feedback Loop; 3.4 The Shim System; 3.5 Tuning and Matching the Probe; 3.6 NMR Data Acquisition and Acquisition Parameters; 3.7 Noise and Dynamic Range; 3.8 Special Topic: Oversampling and Digital Filtering; 3.9 NMR Data Processing-Overview; 3.10 The Fourier Transform; 3.11 Data Manipulation Before the Fourier Transform. - 3.12 Data Manipulation After the Fourier Transform4 Carbon-13 ((13)C) NMR Spectroscopy; 4.1 Sensitivity of (13)C; 4.2 Splitting of (13)C Signals; 4.3 Decoupling; 4.4 Heteronuclear Decoupling: (1)H Decoupled (13)C Spectra; 4.5 Decoupling Hardware; 4.6 Decoupling Software: Parameters; 4.7 The Nuclear Overhauser Effect (NOE); 4.8 Heteronuclear Decoupler Modes; 5 NMR Relaxation-Inversion-Recovery and the Nuclear Overhauser Effect (NOE); 5.1 The Vector Model; 5.2 One Spin in a Magnetic Field; 5.3 A Large Population of Identical Spins: Net Magnetization. - 5.4 Coherence: Net Magnetization in the x-y Plane5.5 Relaxation; 5.6 Summary of the Vector Model; 5.7 Molecular Tumbling and NMR Relaxation; 5.8 Inversion-Recovery: Measurement of T(1) Values; 5.9 Continuous-Wave Low-Power Irradiation of One Resonance; 5.10 Homonuclear Decoupling; 5.11 Presaturation of Solvent Resonance; 5.12 The Homonuclear Nuclear Overhauser Effect (NOE); 5.13 Summary of the Nuclear Overhauser Effect; 6 The Spin Echo and the Attached Proton Test (APT); 6.1 The Rotating Frame of Reference; 6.2 The Radio Frequency (RF) Pulse; 6.3 The Effect of RF Pulses. - 6.4 Quadrature Detection, Phase Cycling, and the Receiver Phase6.5 Chemical Shift Evolution; 6.6 Scalar (J) Coupling Evolution; 6.7 Examples of J-coupling and Chemical Shift Evolution; 6.8 The Attached Proton Test (APT); 6.9 The Spin Echo; 6.10 The Heteronuclear Spin Echo: Controlling J-Coupling Evolution and Chemical Shift Evolution; 7 Coherence Transfer: INEPT and DEPT; 7.1 Net Magnetization; 7.2 Magnetization Transfer; 7.3 The Product Operator Formalism: Introduction; 7.4 Single Spin Product Operators: Chemical Shift Evolution. - 7.5 Two-Spin Operators: J-coupling Evolution and Antiphase Coherence. - NMR Spectroscopy Explained : Simplified Theory, Applications and Examples for Organic Chemistry and Structural Biology provides a fresh, practical guide to NMR for both students and practitioners, in a clearly written and non-mathematical format. It gives the reader an intermediate level theoretical basis for understanding laboratory applications, developing concepts gradually within the context of examples and useful experiments.Introduces students to modern NMR as applied to analysis of organic compounds. Presents material in a clear, conversational style that is appealing
Emner
Sjanger
Dewey
ISBN
9780471730965

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