The behavioral pathology in Alzheimer's disease scale (BEHAVE-AD):Factor structure among community-dwelling Alzheimer's diseasepatients


D.G. Harwood
Bok Engelsk 1998
Utgitt
1998
Omfang
Side 793- 800
Opplysninger
Objective. The aims of this study were to (a) determine the factorstructure of the Behavioral Pathology in Alzheimer's Disease Scale(BEHAVE-AD), and (b) examine the associations of the observed factorsto the level of cognitive impairment.Design. Cross-sectional study of geriatric patients evaluated at anoutpatient memory disorders clinic.Sample. One hundred and fifty-one consecutive patients diagnosed withAlzheimer's disease (AD) according to NINCDS-ADRDA diagnosticcriteria.Results. Principal factors analysis with Varimax rotation resulted ina five-factor solution that accounted for 40.0% of the commonvariance. The factors included agitation/anxiety (agitation, anxietyof upcoming events; other anxiety), psychosis (delusions of theft,suspiciousness/paranoia; visual hallucinations), aggression (verbalaggressiveness; physical threats/violence; fear of being left alone;other delusions), depression (tearfulness; depressed mood) andactivity disturbance (wandering; delusion one's house is not one'shome). Several factors were associated with level of cognitiveimpairment as assessed by the Mini-Mental State Examination (MMSE).Conclusion. The results of this study suggest that the BEHAVE-ADmeasures a wide range of behavioral pathology that can be empiricallyrepresented by five independent symptom clusters among outpatient ADpatients. (C) 1998 John Wiley & Sons, Ltd.
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