Natural history of hyperphagia and other eating changes in dementia
J. Keene
Bok Engelsk 1998
| Utgitt | 1998
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| Omfang | Side 700- 706
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| Opplysninger | Objective. To investigate the natural history of overeating(hyperphagia) and its elements during the course of dementia.Design. Prospective longitudinal study of overeating (hyperphagia) indementia. Two studies were carried out: (1) hyperphagia andassociated eating changes were investigated as part of a largerprospective 10-year study into behaviour changes, using carers'reports; (2) an observational study to investigate hyperphagiaquantitatively; this took place over the course of a year by means ofdirect observation of test meals in a normal environment.Setting. Subjects with dementia living in Oxfordshire, UK.Participants (1) 99 people with dementia, living at home with acarer, with data for more than 1 year. (2) Nine people with adiagnosis of Alzheimer's disease who were hyperphagic.Measures. (1) The Present Behavioural Examination was used at 4-monthly intervals to assess the subjects' behaviour and psychologicalfunctioning. (2) Food intake, macronutrient choice and themicrostructure of eating were measured using a standardized testmeal.Results. (1) Severe or persistent hyperphagia was reported in 23% ofthe sample and carers reported a clear onset to hyperphagia with amedian duration of 16 months. (2) From direct observation, eachperson who was hyperphagic was seen to maintain a constant eatingrate in test meals during the course of a year but meals endedearlier as hyperphagia decreased.Conclusions. Hyperphagia is common in dementia, it occurs over asingle restricted period, mainly during the middle stages ofdementia, and is not significantly related to age, sex, diagnosis,medication or activity. (C) 1998 John Wiley & Sons, Ltd.
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