Tryptophan and nutritional status of patients with senile dementia.
DE Thomas
Bok Engelsk 1986
| Utgitt | 1986
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| Opplysninger | The nutritional status of 23 severely demented patients was compared with that of 23 similarly aged controls in the community. A3-day weighed intake on all subjects showed lower mean intakes ofenergy, protein, ascorbic acid and nicotinic acid in the mean intakes of energy, protein, ascorbic acid and nicotinic acid in the patient group.This group had lower levels of plasma ascorbic acid and red cell folate and of urinary N-methylnicotinamide excretion relative to creatinine.Over a third of both controls and patients had evidence of thiamin deficiency, as judged by a raised percentage erythrocyte transketolase activity. An earlier finding in patients with senile dementia of reduced fasting plasma concentrations of tryptophan was confirmed for total and protein bound fractions. With the possible exception of ascorbic acid,the data could not be explained satisfactorily in terms of intake. It is suggested that the association between the phenomena of aging, senile dementia and nutritional status merits further investigation.
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| Emner | Aldring
Demens Ernæring Hjernen Vis mer... (50-67-9 (Serotonin))
(6912-86-3 (Tryptophan)) Ascorbic Acid Deficiency/COMPLICATIO Brain/METABOLISM Caloric Intake Deficiency Diseases/BLOOD/COMPLICATIONS Dementia, Senile/BLOOD Dietary Proteins/ADMINISTRATION & DOSAGE Energy Metabolism Folic Acid Deficiency/COMPLICATIONS Nutritional Requirements Protein Binding Serotonin/DEFICIENCY Tryptophan/BLOOD Vitamin D Deficiency/COMPLICATIONS |
