Factors associated with a depressive disorder in Alzheimer’s Disease are different from those found for other dementia disorders
Maria Lage Barca, Knut Engedal, Jerson Laks, Geir Selbæk
Bok Engelsk 2012
| Utgitt | 2012
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| Omfang | 9 s.
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| Opplysninger | Background: This study explores factors associated with depression in Alzheimer’s disease (AD) compared with mild cognitive impairment (MCI) and other dementia disorders. Method: In a prospective study we included 195 patients: 31 with MCI, 112 with AD and 52 with other dementias. Results: According to the ICD-10 and the DSM-IV criteria, 88 (44.1%) and 59 (30.3%), respectively, had a depressive disorder. An adjusted multiple regression analysis showed that previous depression (p < 0.05) was significantly associated with depression in AD patients. Severity of dementia (p < 0.05) was significantly associated with a depressive disorder in a group of patients with frontotemporal dementia, vascular dementia, or dementia due to Lewy Body disease or Parkinson’s disease. Conclusion: We found different factors associated with a depressive disorder in AD compared to those found for other dementia disorders.
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