Alzheimer's disease. Morbid risk among first-degree relatives approximates 50% by 90 years of age.
Mohs RC
Bok Engelsk
| Omfang | 4 s.
|
|---|---|
| Utgave | Kopi
|
| Opplysninger | The morbid risk of Alzheimer's disease was studied infirst-degree relatives of 50 patients who met contemporary clinicalresearch diagnostic criteria and 45 matched controls. Relativesof patients showed a 46% cumulative incidence of probable Alzheimer'sdisease by 86 years of age. The risk, which was four times the control value,is consistent with other recent reports using similar, modern methods.Although not conclusive, the data suggest the operation of arelatively common, dominant autosomal gene for Alzheimer's disease, theexpression of which is delayed until late old age but is largely complete by90 years of age.
|
| Emner |
