Predictors of retrograde amnesia following ECT
Christina et al Sobin
Bok Engelsk
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| Opplysninger | CONCLUSIONS: Patients who manifest global cognitive imipairment before treatment and patients who experience prolonged disorientation in the acute postictal period may be the most vulnerable to persistent retrograde amnesia for autobiographical information.. - METHOD: Seventy-one inpatients with major depressive disorder were randomly assigned to four ECT conditions that varied in electrode placement (right unilateral versus bilateral) and stimulus dosage (low versus high itensity). Orientation recovery time was assessed at virtually every session during the course of ECT. Global cognitive status was assessed at these same time points with the Autobiographical Memory Interview.. - OBJECTIVE: Substantial progress has been made in identifying how the treatment parameters used in ECT impact on cognitive side effects. However, there is limited information regarding individual differences in vulnerability ti these side effects. The authors examined patients' pretreatment global cognitive status and postictal orientation recovery time as potential predictors of the magnitude of retrograde amnesia for autobiographical memories after ECT.. - RESULTS: Pre-ECT global cognitive status and the duration of postictal disorientation were strong predictors of teh magnitude of retrograde amnesia in the week after the course of ECT and at 2-month follow-up. In general, these relationships were maintained regardless of technical param,eters in the administration of the ECT.
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