Risk Factors Among Incident Cases of Dementia in a Representative British Sample


J.M. Lilley
Bok Engelsk
Utgitt
K Morgan Univ Nottingham Sch Med Dept Hlth C
Omfang
5 s.
Opplysninger
AbstractIn a 4-year follow up of 1042 elderly people (aged 65+) randomly sampled from the community, levels of dementia were assessed using a two-phase case-finding procedure (screening followed by clinical interwiev) among survivors, with additional information provided by death certificates, hospital case notes or postal questionnaires. Overall, 42 cases were clinically identified. In case-control analysis matching for age, sex and premorbid cognitive status, risk estimates were obtained for nine self-reported factors: heart trouble; headaches; giddiness; falls, current smoking; past smoking; left-handedness; insomnia; and the use of sedative-hypnotic drugs to promote sleep. While none of these factors was associated with a significantly increased risk, the power of these case-control comparisons was limited by sample size.
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