Finding signals in the noise : immunoaffinity smart samplers for LC-MS/MS analysis
Christina Johannsen
Bok · Engelsk · 2025 · Doktoravhandlinger
Tekstet på: Engelsk, Bokmål, Tysk
| Omfang | 1 bind (varierende paginering) : illustrasjoner
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| Opplysninger | Delvis opptrykk av artikler. - Avhandling (Ph.D) - Universitetet i Oslo, 2025. - Immunoaffinity Smart Samplers for LC-MS/MS Analysis / Christina Johannsen -- Development of Smart Samplers for Blood Purification / Christina Johannsen -- Applications of Smart Samplers in Therapeutic Drug Monitoring / Christina Johannsen -- Challenges in Smart Sampler Technology / Christina Johannsen -- Future Directions for Smart Sampler Research / Christina Johannsen. - \"Most blood tests today require venous blood draws, which can be invasive and require skilled healthcare personnel. This PhD thesis explores a new alternative: smart samplers. Simple devices that can be integrated into wearable formats, smart samplers utilize a filter that purifies blood or urine with antibodies that capture unique target analytes for LC-MS/MS analysis. Smart samplers are currently in the early stages of development and testing, but their potential for simplifying diagnostics and therapeutic drug monitoring is promising. Smart samplers have the potential to be used in a variety of settings, from clinics to homes, offering a less invasive and more accessible method for obtaining samples. The technology is expected to greatly improve the reliability and ease of sample collection, paving the way for blood draws to be replaced by smart samplers, which can potentially change the medical field.\"
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