Craniofacial Sutures : Development, Disease and Treatment


D.P. Rice
Bok Engelsk 2008 · Electronic books.
Annen tittel
Utgitt
Basel : : Karger Publishers, , 2008.
Omfang
1 online resource (249 p.)
Opplysninger
Description based upon print version of record.. - Cover; Contents; Foreword; Preface; Developmental Anatomy of Craniofacial Sutures; Locate, Condense, Differentiate, Grow and Confront: Developmental Mechanisms Controlling Intramembranous Bone and Suture Formation and Function; Mechanical Influences on Suture Development and Patency; Suture Neontology and Paleontology: The Bases for Where, When and How Boundaries between Bones Have Been Established and Have Evolved; Single Suture Craniosynostosis: Diagnosis and Imaging; Clinical Features of Syndromic Craniosynostosis. - Genetics of Craniosynostosis: Genes, Syndromes, Mutations and Genotype-Phenotype CorrelationsRoles of FGFR2 and Twist in Human Craniosynostosis: Insights from Genetic Mutations in Cranial Osteoblasts; Fibroblast Growth Factor Signaling in Cranial Suture Development and Pathogenesis; Tgf-ß Regulation of Suture Morphogenesis and Growth; The Bmp Pathway in Skull Vault Development; Current Treatment of Craniosynostosis and Future Therapeutic Directions; Author Index; Subject Index. - Sutures are more than just fibrous joints between the bones in our skull. They are active growth sites that influence the development, growth and shaping of our face and cranium. When suture development is disrupted, craniosynostosis can result, a condition which is characterized by the premature closure of one or more cranial sutures before brain growth is complete and leads to an abnormally shaped skull. In this publication, leading experts in the field, both researchers and clinicians, discuss suture morphogenesis from developmental, evolutionary and genetic perspectives. In addition, an ap
Emner
Sjanger
Dewey
ISBN
9783805583268

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