Association between depression and cognitive impairment in aged malewar veterans. 2(4).
O.F. Dent
Bok Engelsk 1998
| Utgitt | 1998
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|---|---|
| Omfang | 306- 312
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| Opplysninger | This study examined the association between both depressive symptomsand depressive disorder and subsequent cognitive performance andincident dementia. Participants were selected randomly from maleveterans of World War II living in Sydney, Australia in 1982 (n =342). Those surviving were interviewed again in 1991 (12 = 209).Depressive disorder and dementia were diagnosed clinically.Depressive symptoms were assessed by a standard self-completed scale.Cognitive performance was assessed by 18 standard neuropsychologicaltests representing a range of mental functions. There was essentiallyno predictive and no concurrent association between depressivedisorder and cognitive performance. There was a marginal correlationbetween depressive disorder in 1982 and dementia in 1991 but noconcurrent association in 1991. Initially, depressive symptomsappeared to be associated with cognitive impairment, bothpredictively and concurrently. However when verbal intelligence wascontrolled, the predictive association disappeared for all but twocognitive performance tests and the concurrent association weakeneddistinctly across all tests. We concluded that cognitive performanceand incident dementia were not predicted by depressive disorder norby depressive symptoms after adjusting for the effect ofintelligence.
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| Emner |
