The overlap between Alzheimer's disease and vascular dementia: Therole of white matter changes
A. Wallin
Bok Engelsk 1998
Utgitt | 1998
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Omfang | Side 30- 35
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Opplysninger | As there is some overlap between Alzheimer's disease (AD) andvascular dementia (VaD), it can be assumed that some particularfeatures that they have in common are responsible for this overlap.One of the candidates is white matter changes whose presence invariants of the two entities is described in this paper. A common,although much debated: division of AD is into two types, type Iusually with early and type II usually with late onset. As to VaD,the division can be based on neuropathological changes and vasculardisease mechanisms. In one subtype, 'subcortical white matterdementia', white matter lesions are conspicuous features. The overlapbetween this subtype and AD type I is small, but the overlap isconsiderable between the same subcortical subtype and AD type II. Inthe latter, white matter changes and Alzheimer encephalopathy mayinteract to produce dementia.
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Emner |