Prevalence and clinical correlates of psychotic symptoms inAlzheimer's disease


N. Gormley
Bok Engelsk 1998
Utgitt
1998
Omfang
Side 410- 414
Opplysninger
Psychotic symptoms occur commonly in Alzheimer's disease (AD),predict a more rapid rate of cognitive decline and increase the riskof aggressive behaviour. Seventy patients with probable AD, recruitedfrom an old age psychiatry service, were assessed to determine theprevalence and clinical correlates of delusions and hallucinations.Psychiatric symptoms were measured using the Behavioural Pathology inAlzheimer's Disease Rating Scale (BEHAVE-AD), Hamilton Rating Scalefor Depression (HRSD) and the Depressive Signs Scale (DSS). Thirty-four per cent of the sample experienced delusions and 11%hallucinations in the previous month. Men were more likely than womento have experienced psychotic symptoms. Psychotic and non-psychoticgroups did not differ in age, age at illness onset, dementiaseverity, HRSD or DSS scores. This study confirms the high prevalenceof psychotic symptoms in AD patients encountered in clinicalpractice, and suggests that psychosis and depression representindependent behavioural disturbances in AD. (C) 1998 John Wiley &Sons, Ltd.
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