Explicit memory in frontotemporal dementia: The role of medialtemporal atrophy
I. Lavenu
Bok Engelsk 1998
| Utgitt | 1998
|
|---|---|
| Omfang | Side 99- 102
|
| Opplysninger | In our memory clinic experience, memory impairment differs widely inpatients with frontotemporal dementia (FTD). We searched for acorrelation between explicit memory disturbance assessed with theGrober and Buschke test and medial temporal atrophy on CT scan in 22consecutive patients with FTD. Five of the 22 patients had a medialtemporal lobe (MTL) atrophy. There was no significant differencebetween the two groups for the demographic characteristics. Freerecall, cued recall and the learning curve were significantly betterin patients without MTL atrophy. The patients with MTL atrophy mademore intrusions. We found a positive correlation between total recalland cued recall and the mean of medial temporal lobe measurement.These results are in agreement with the role of the hippocampalformation in the memory process. In our group, the ratio of patientswith MTL atrophy is similar to the ratio of Pick's disease infrontotemporal dementia. In histological series more severehippocampal atrophy are reported in Pick's disease. Therefore MTLatrophy on CT scan could be a marker of Pick's disease in FTD.
|
| Emner |
