The effects of preclinical dementia on estimates of normal cognitivefunctioning in aging


M. Sliwinski
Bok Engelsk 1996
Utgitt
1996
Omfang
Side P217- P225
Opplysninger
Individuals with preclinical dementia have begun to declinecognitively, but still perform within normal limits on cognitivetesting. As a group, subjects with preclinical dementia have lowerscores on neuropsychological tests than their dementia-freecounterparts. This study examines the effects of preclinical dementiaon estimates of normal cognitive function in the aged using data froma longitudinal study. Individuals with preclinical dementia atbaseline were retrospectively identified based on subsequentdevelopment of dementia. Age-adjusted norms were computed usingbaseline data for the Selective Reminding Test and the WAIS verbaland performance scores, both including (conventional norms) and thenexcluding (robust norms) preclinical cares. The results indicate thatby foiling to exclude preclinical dementia, conventional normativestudies underestimate the mean, overestimate the variance, andoverestimate the effect of age on cognitive measures. Methods arediscussed for selecting robust elderly samples that are relativelyfree of contamination by preclinical dementia.
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