Incidence of dementia in a Munich community sample of the oldest old


M.M. Fichter
Bok Engelsk 1996
Utgitt
1996
Omfang
Side 320- 328
Opplysninger
In a two-wave community study a representative sample of 402 very oldpeople (older than 85 years) was restudied 1 year later. Fourinstruments in the clinical examination were used for caseidentification: (a) the Geriatric Mental State Interview (GMS-A); (b)the Structured Interview for the Diagnosis of Dementia (SIDAM); (c)the Global Deterioration Scale (GDS); and (d) the Mini Mental StateExamination (MMSE). The clinical examination was performed by theinterviewing physician who made a diagnosis according to DMS-III-R.The focus of the present study is on the (true) incidence. Ofdementia in a representative community sample. The establishment ofincidence rates is particularly important for dementia because theprevalence of dementia is affected by the length of survival, whichis reduced in dementia and with increasing age. The annual incidencerates per 1000 person years on the basis of the SIDAM DSM-III-R were116.6 for all cases at risk, 113.6 for those aged 85-89 years, 113.5for those aged 90-94 years and 235.7 for those aged 95 years andolder at first assessment (t(l)). Incidence rates based on the othermethods of assessment are reported. In order to obtain the mostmeaningful estimate of incidence rates a compound dementia diagnosiswas defined. According to this the annual incidence rate per 1000person years was 144.1 for all persons at risk. The incidence rate;ended to be higher in the older-age cohorts: It was 136.2 for thoseaged 85-89 years, 193.1 for those aged 90-93 years and 295.5 forthose aged 95 years and older. In comparison with the literature theincidence rates were high. The results are plausible when the veryold age of the sample is taken into account.
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