Determination of selected trace elements in patients affected bydementia
M. Molaschi
Bok Engelsk 1996
| Utgitt | 1996
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|---|---|
| Omfang | Side 39- 42
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| Opplysninger | The relationship between dementia and trace elements is widelydebated. Neurotoxicity of aluminium is well recognized. The purposeof the study was to evaluate serum levels of a few trace elements anda few serum proteins in demented subjects. The study was carried outon 452 women, age range 73 - 88 years. Thirty one of them wereaffected by dementia of Alzheimer type in early or middle stages. Thediagnosis had been performed by history, physical and instrumentalexaminations, as well as by psychometric tests. The followingparameters were determined: iron zinc, copper, serum albumin,transferrin, ceruloplasmin. Iron, copper and zinc are somewhat lowerin demented subjects than in controls, but the differences arestatistically not significant. The slightly diminished levels ofserum albumin and transferrin in the study group may be related to amild malnutrition. The reduction of the proteins binding traceelements, particularly of transferrin. Could cause a higherbioavailability of neurotoxic trace elements such as aluminium.
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| Emner |
