Epidemiology of Alzheimer's disease and current possibilities forprevention
L. Fratiglioni
Bok Engelsk 1996
| Utgitt | 1996
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|---|---|
| Omfang | Side 33- 40
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| Opplysninger | Many epidemiological studies of Alzheimer's disease (AD) have beenconducted. This review discusses the most recent findings in relationto the possibilities of prevention of this disease. Data on thediagnostic validity are also reported. The primary prevention of ADis hampered by limitations in the knowledge and understanding aboutits risk factors. Among the factors that have been investigated, onlyage, familial aggregation, and apolipoprotein E gene-e4 allele aredefinite risk factors both for early- and late-onset AD. However,many of the possible and putative risk factors, if definitelyconfirmed, can be prevented or controlled. Secondary prevention isnot currently practicable as valid predictive tests and efficacioustreatment are lacking. In contrast, much data is available to supporttertiary prevention interventions, such as better planned patientcare.
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| Emner |
