Depression does not aggravate the episodic memory deficits associated with Alzheimer`s Disease
Anna-Karin Berger, Kjell Fahlander, Åke Wahlin, Lars Bäckman
Bok Svensk 2004
| Utgitt | 2004
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|---|---|
| Omfang | 7 s.
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| Opplysninger | In a population-based study of persons between 75 and 96 years ofage,normal old adults (n = 296), patients with Alzheimer's disease (AD: n = 45), and patients with concomitant AD and depression (AD-D: n = 9) were compared on free recall and recognition of slowly and rapidly presented words and digit span. With the exception of forward digit span, the normal old group outperformed the 2 AD groups across all tasks. In free recall, only the normal old group performed better as task pacing decreased: however, all groups benefited from more study time in recognition. This suggests that both AD and AD-D patients have deficits in the ability to use more study time for remembering. Of most importance, the 2 AD groups were indistinguishable for all task variables. This lack of comorbidity effects is discussed relative to the view that depression, much like many other individual-difference variables that affect memory performance in normal aging, may be overshadowed by the influence of the neurodegenerative process in AD.
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