Functional activation of the frontal lobes : Regional cerebral blood flow findings in normals and in patients with frontal lobe dementia performing a word fluency test
Siegbert Warketin
Bok Engelsk 1993
| Utgitt | 1993
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| Omfang | 5 s.
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| Utgave | Særtrykk
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| Opplysninger | Abstract: The present study examined the utility of the Word Fluency Testn(WFT) as a frontal-lobe-activating test in brain imaging. regional cerebral blood flow (rCBF) was measured during rest and during the WFT in 49 healthy volunteers and in 15 patients with frontal lobe dementia (FLD). The results showed a highly significant frontal lobe activation in 85% of the normal subjects. This finding was not related to age or to tha level of performance of the WFT. A significant frontal activation was seen in 13 of the 15 FLD patients. The frontal flow increase did not reach normal levels, and was not related to age, illness duration or severity of clinical symptoms. the results suggest that the WFT is an ideal test to use in conjunction with functional imaging in normals as well as in patients with organic dementia.
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